Loss of Stearoyl-CoA Desaturase-1 Attenuates Adipocyte Inflammation
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چکیده
منابع مشابه
Loss of Stearoyl-CoA desaturase-1 attenuates adipocyte inflammation: effects of adipocyte-derived oleate.
BACKGROUND AND PURPOSE Adipose inflammation is crucial to the pathogenesis of metabolic disorders. This study aimed at identify the effects of stearoyl-CoA desaturase-1 (SCD1) on the inflammatory response of a paracrine network involving adipocytes, macrophages, and endothelial cells. METHODS AND RESULTS Loss of SCD1 in both genetic (Agouti) and diet-induced obesity (high-fat diet) mouse mode...
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ژورنال
عنوان ژورنال: Arteriosclerosis, Thrombosis, and Vascular Biology
سال: 2010
ISSN: 1079-5642,1524-4636
DOI: 10.1161/atvbaha.109.195636